Blar i forfatter "Isaksen, Jørgen Gjernes"

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    • Anatomical variations in the circle of Willis are associated with increased odds of intracranial aneurysms: The Tromsø study 

      Hindenes, Lars Bakke; Ingebrigtsen, Tor; Isaksen, Jørgen Gjernes; Håberg, Asta; Johnsen, Liv-Hege; Herder, Marit; Mathiesen, Ellisiv B.; Vangberg, Torgil Riise (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-25)
      Purpose: Studies on patients suggest an association between anatomical variations in the Circle of Willis (CoW) and intracranial aneurysms (IA), but it is unclear whether this association is present in the general population. In this cross-sectional population study, we investigated the associations between CoW anatomical variations and IA.<p> <p>Methods: We included 1667 participants from a ...

    • Cerebral aneurysm morphology before and after rupture: nation-wide case series of 29 aneurysms 

      Skodvin, Torbjørn Øygard; Johnsen, Liv-Hege; Gjertsen, Øivind; Isaksen, Jørgen Gjernes; Sorteberg, Angelika (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-06)
      <p><i>Background and Purpose</i>: Using postrupture morphology to predict rupture risk of an intracranial aneurysm may be inaccurate because of possible morphological changes at or around the time of rupture. The present study aims at comparing morphology from angiograms obtained prior to and just after rupture and to evaluate whether postrupture morphology is an adequate surrogate for rupture ...

    • A fully-coupled fluid-structure interaction simulation of cerebral aneurysms 

      Isaksen, Jørgen Gjernes; Bazilevs, Yuri; Hsu, M. C.; Zhang, Y.; Wang, W.; Liang, X; Kvamsdal, Trond; Brekken, Reidar (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)

    • Outcome of aneurysmal subarachnoid hemorrhage in a population-based cohort: Retrospective registry study 

      Iversen, Mathilde Vea; Ingebrigtsen, Tor; Totland, Jon Andre; Kloster, Roar; Isaksen, Jørgen Gjernes (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-29)
      BACKGROUND: Studies of aneurysmal subarachnoid hemorrhage report an association between higher patient volumes and better outcomes. In regions with dispersed settlement, this must be balanced against the advantages with shorter prehospital transport times and timely access. The aim of this study is to report outcome for unselected aneurysmal subarachnoid hemorrhage cases from a well-defined rural ...

    • Prevalence of intracranial artery stenosis in a general population using 3D-time of flight magnetic resonance angiography 

      Johnsen, Liv-Hege; Herder, Marit; Vangberg, Torgil Riise; Isaksen, Jørgen Gjernes; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-20)
      Background: Data on prevalence of intracranial artery stenosis (ICAS) in Western populations is sparse. The aim of the study was to assess the prevalence and risk factors for ICAS in a mainly Caucasian general population. Methods: We assessed the prevalence of ICAS in 1847 men and women aged 40 to 84 years who participated in a cross-sectional population-based study, using 3-dimensional time-of-flight ...

    • Prevalence of unruptured intracranial aneurysms: impact of different definitions-the Tromsø Study 

      Johnsen, Liv-Hege; Herder, Marit; Vangberg, Torgil Riise; Kloster, Roar; Ingebrigtsen, Tor; Isaksen, Jørgen Gjernes; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-10)
      Background - Management of incidental unruptured intracranial aneurysms (UIAs) remains challenging and depends on their risk of rupture, estimated from the assumed prevalence of aneurysms and the incidence of aneurysmal subarachnoid haemorrhage. Reported prevalence varies, and consistent criteria for definition of UIAs are lacking. We aimed to study the prevalence of UIAs in a general population ...

    • Prompt closure versus gradual weaning of external ventricular drainage for hydrocephalus following aneurysmal subarachnoid haemorrhage: Protocol for the DRAIN randomised clinical trial 

      Capion, Tenna; Lilja-Cyron, Alexander; Olsen, Markus Harboe; Juhler, Marianne; Moeller, Kirsten; Sorteberg, Angelika; Rønning, Pål Andre; Poulsen, Frantz Rom; Wismann, Joakim; Ravlo, Celina; Isaksen, Jørgen Gjernes; Lindschou, Jane; Gluud, Christian; Mathiesen, Tiit (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-10)
      Background: Aneurysmal subarachnoid haemorrhage (aSAH) is a life-threatening disease caused by rupture of an intracranial aneurysm. A common complication following aSAH is hydrocephalus, for which placement of an external ventricular drain (EVD) is an important first-line treatment. Once the patient is clinically stable, the EVD is either removed or replaced by a ventriculoperitoneal shunt. The ...

    • Survey of European neurosurgeons’ management of unruptured intracranial aneurysms: inconsistent practice and organization 

      Skodvin, Torbjørn Øygard; Kloster, Roar; Sorteberg, Wilhelm; Isaksen, Jørgen Gjernes (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-01)
      Background - The discovery of an unruptured intracranial aneurysm creates a dilemma between observation and treatment. Neurosurgeons’ routines for risk assessment and treatment decision-making are unknown. The position of evidence-based medicine in European neurosurgery is considered to be weak, high-grade guidelines do not exist and variations between institutions are probable. We aimed to explore ...